Hong Kong's Hang Seng index led the losses and was down by more than 1 per cent after police fired live rounds at protestors on the eastern side of Hong Kong island.
Among the gainers were pharma majors like Cipla, Dr Reddy's and Sun Pharma besides Yes Bank, Mahindra & Mahindra, Tech Mahindra, Coal India and Bharat Petroleum Corporation.
MSCI's broadest index of Asia Pacific shares outside Japan ticked up by 0.1 per cent after hitting a four-month high the previous day.
