Britannia slipped by 2.7 per cent while Nestle India lost by 1.6 per cent. The other prominent losers were Bharat Petroleum Corporation, ONGC, Kotak Mahindra Bank, Bharti Airtel and Wipro.
The other prominent winners were Infosys, HCL Technologies, GAIL and ICICI Bank. However, Sun Pharma and Hindustan Lever traded with a negative bias.
IndusInd Bank too lost by 2.8 per cent after it reported 77 per cent sequential decline in standalone net profit at Rs 302 crore during the quarter ended March.
Meanwhile, Asian shares fell on doubts about progress in the development of drugs to treat COVID-19 and new evidence of US economic damage caused by the coronavirus pandemic.
Meanwhile, Asian stock markets rose with a rebound in crude prices from historic lows and the promise of more US government aid to absorb the economic impact of coronavirus pandemic.
Meanwhile, Asia shares were in the negative zone after an overnight tumble at Wall Street with US crude futures turned negative for the first time in history. However, it bounced back into positive territory on Tuesday.
Meanwhile, Asian share markets were cautious on expectations of a busy week of corporate earnings reports and economic data.
However, index heavyweight Reliance Industries gained by 2.36 per cent to Rs 1,177 per share. Vedanta, UPL, Larsen & Toubro and Power Grid Corporation too traded with a positive bias.
MSCI's broadest index of Asia Pacific shares outside Japan lost by 0.7 per cent but Japan's Nikkei added 0.4 per cent while Shanghai blue chips lost by 0.6 per cent.
Shares in China rose by 0.18 per cent and in South Korea by 0.19 per cent. But Japanese shares fell by 1.05 per cent as a rapid increase in coronavirus infections in Tokyo fuelled speculation the government will place the capital on lockdown.